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The recommended approach is to try conservative management strategies first (cool compresses, antihistamines, clothing changes), then consider dose adjustment if symptoms persist beyond 4 weeks, and only discuss discontinuation if symptoms are severe and unresponsive to other interventions

Factor in bacteriostatic water ($8-15 per vial), syringes ($15-30 for a box), alcohol swabs ($5-10), and potentially cold shipping surcharges ($15-30 during warm months)

Any deviation from established storage and handling practices can compromise research integrity, making results difficult to reproduce or compare

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